Levitra Professional: A Detailed Examination

Characteristic	Details
Active Ingredient	Vardenafil
Available Dosages	10 mg, 20 mg
Formulation	Oral tablet
FDA Approval Year	2003
Time to Effect	30 to 60 minutes
Duration of Effect	4 to 5 hours
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Pharmacokinetics

Levitra Professional showcases unique pharmacokinetic properties. Vardenafil 20 mg, its active agent, is absorbed rapidly. Peak plasma levels are attained within 30 to 120 minutes post-ingestion. The bioavailability hovers around 15%, influenced by high-fat meals which delay absorption. The metabolic pathway relies heavily on CYP3A4, with minor contributions from CYP2C9. This impacts clearance rates. Excretion involves both renal and fecal routes, with the latter being predominant. The terminal half-life is approximately four to five hours, supporting its efficacy window.

Levitra Professional Use

Levitra Professional addresses erectile dysfunction in adult males. Its use results in improved penile rigidity and erection maintenance. A single Levitra Professional 20 mg dose enhances erectile function significantly. Sexual stimulation is necessary for its action. Prescribers recommend ingestion approximately 60 minutes before sexual activity. Patients may consume it with or without food, yet fatty meals may slow its effect. Physicians must evaluate cardiovascular status due to potential hemodynamic changes during coitus.

FDA-Approved Indications

The U.S. Food and Drug Administration endorses Levitra Professional for erectile dysfunction treatment. The clinical trials underpinning this approval involved men aged 18 to 85. Participants exhibited significant improvements in International Index of Erectile Function scores. The FDA’s decision reflects a favorable balance of efficacy and safety. Contraindications include concurrent nitrate therapy, as vardenafil may potentiate hypotensive effects. Further, caution is advised in those with severe hepatic impairment.

Missed Dose

Levitra Professional is consumed on an as-needed basis, eliminating concerns of a missed dose. Users should not exceed one dose within a 24-hour frame. If a dose is missed, it should not be doubled at the next intake. Overdosing heightens the risk of adverse effects. Patients with chronic conditions should adhere to prescriber advice, particularly when adjusting dosage frequency. The prescribing healthcare professional remains a crucial resource for patient-specific guidance.

Signs and Symptoms of Overdose

Overdose manifests through severe side effects. Common symptoms include dizziness, syncope, and tachycardia. Priapism is a serious concern, warranting immediate medical intervention if erections persist beyond four hours. Visual disturbances and severe headaches may also occur. Prompt consultation with a healthcare provider is essential in such events. Management involves symptomatic treatment and close monitoring of vital signs. Vardenafil-specific antidotes remain unavailable, reinforcing the importance of cautious dosing.

Levitra Professional for Sale Online

The digital marketplace offers wide access to Levitra Professional. Online acquisition necessitates vigilance. Authenticity and quality assurance of the product are paramount. Consumers should seek reputable pharmacies verified by regulatory bodies. The U.S. National Association of Boards of Pharmacy’s Verified Pharmacy Program serves as a reliable reference. Additionally, legal considerations must guide purchasing decisions, ensuring compliance with national healthcare regulations.

Potential Side Effects	Occurrence Rate
Headache	Common
Flushing	Common
Nasal Congestion	Uncommon
Dizziness	Uncommon
Vision Disturbance	Rare

Assess patient history before prescription.
Instruct users on correct administration timing.
Highlight importance of recognizing overdose symptoms.
Advise against combining with nitrates.
Recommend purchasing from certified online sources.

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